| 1st Melbourne Cell Biology Signalling Meeting |
| Morning Session I: |
Chair: Prof Suresh Mathivanan (La Trobe University) |
| 9:00 – 9:10 |
Welcome: Prof Andy Hill (Director, LIMS, La Trobe University) |
| 9:10 – 9:40 |
Chair: Dr Amy Baxter (La Trobe University) |
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Keynote Speaker: Kanaga Sabapathy (National Cancer Centre, Singapore) |
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Targeting p53 |
| 9:40 – 10:05 |
Chair: Dr Ashwini Chand (ONJCRI) |
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Invited Speaker: Christine Chaffer (Garvan Institute of Medical Research) |
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Modulating cancer cell plasticity to inhibit metastasis |
| 10:05 – 10:30 |
Morning tea [+trade display] |
| Morning Session II: |
Chairs: Prof John Mariadason (ONJCR), Dr Diana Stojanovski (Melbourne University) |
| 10:30 – 10:55 |
Invited Speaker: Lee Wong (Monash University) |
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Mutant histone H3.3 and ATRX loss: drivers of Alternative Lengthening of Telomere in cancers |
| 10:55 – 11:10 |
Benjamin L. Parker (University of Melbourne) |
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Cross-species screening of exercise-signalling and exercise-mimetics reveals conserved functional phosphorylation and drug interactions |
| 11:10 – 11:25 |
Thanh Nguyen (Monash University) |
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Identification of a novel function of the mammalian Atg4 family during PINK1/Parkin mitophagy |
| 11:25 – 11:40 |
Hugh Ma (Monash University) |
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Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation |
| 11:40 – 11:55 |
Ashleigh Solano (University of Melbourne) |
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Mapping DNA target search in the nucleus of a living cell by pair correlation of molecular brightness microscopy |
| 11:55 – 12:10 |
Joanne Hildebrand (WEHI) |
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Missense mutations in the MLKL brace region lead to lethal neonatal inflammation in mice and are present in high frequency in humans |
| 12:10 – 1:30 |
Lunch + Poster Session A [+trade display] |
| Afternoon Session I: |
Chairs: Dr Vihandha Wickramasinghe (Peter Mac), Dr Lan Nguyen (Monash University) |
| 1:30 – 1:55 |
Invited Speaker: Jennifer Zenker (ARMI) |
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Live imaging of microtubule remodelling controlling early mammalian development |
| 1:55 – 2:10 |
Ashleigh Poh (ONJCRI) |
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Co-targeting macrophages to improve anti-tumour responses to immunotherapy |
| 1:10 – 2:25 |
Yilin Kang (University of Melbourne) |
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Complex IV defects and oxidative stress underpin neuronal cell death in a neurodegenerative syndrome |
| 2:25 – 2:40 |
William Smiles (St. Vincent's Institute) |
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Palmitoyl-CoA Regulates Drp1 and Mitochondrial Fission by a Structural Mechanism Shared Amongst Metabolic Enzymes |
| 2:40 – 2:55 |
Ishara Atukorala (La Trobe University) |
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Extracellular vesicles in cross-species communication, metastasis and cancer progression |
| 2:55 – 3:55 |
Afternoon tea + Poster Session B [+trade display] |
| Afternoon Session II: |
Chair: A/Prof Jon Oakhill (St Vincent's Institute), Dr Michael Roy (WEHI) |
| 3:55 – 4:20 |
Invited Speaker: Delphine Merino (ONJCRI) |
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Tracking and targeting aggressive clones in metastatic triple negative breast cancer |
| 4:20 – 4:35 |
Marta Portela Esteban (La Trobe University) |
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WNT vampirization by glioblastoma promotes JNK/MMPs positive feedback loop to mediate glioma progression and neurodegeneration |
| 4:35 – 4:50 |
Haiyin Liu (University of Melbourne) |
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Mechanism of cell surface MHC II regulation |
| 4:50 – 5:20 |
Keynote Speaker: David Komander (WEHI) |
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Ubiquitin signals in mitophagy |
| 5:20 – 5:30 |
Closing and awards: Dr Doug Fairlie (ONJCRI) |
