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1st Melbourne Cell Biology Signalling Meeting
Morning Session I:  Chair: Prof Suresh Mathivanan (La Trobe University)
9:00 – 9:10 Welcome: Prof Andy Hill (Director, LIMS, La Trobe University)
9:10 – 9:40 Chair: Dr Amy Baxter (La Trobe University)
  Keynote Speaker: Kanaga Sabapathy (National Cancer Centre, Singapore)
  Targeting p53
9:40 – 10:05 Chair:  Dr Ashwini Chand (ONJCRI)
  Invited Speaker: Christine Chaffer (Garvan Institute of Medical Research)
  Modulating cancer cell plasticity to inhibit metastasis
10:05 – 10:30 Morning tea [+trade display]
Morning Session II:  Chairs: Prof John Mariadason (ONJCR), Dr Diana Stojanovski (Melbourne University)
10:30 – 10:55 Invited Speaker: Lee Wong (Monash University)
  Mutant histone H3.3 and ATRX loss: drivers of Alternative Lengthening of Telomere in cancers
10:55 – 11:10 Benjamin L. Parker (University of Melbourne)
  Cross-species screening of exercise-signalling and exercise-mimetics reveals conserved functional phosphorylation and drug interactions
11:10 – 11:25 Thanh Nguyen (Monash University)
  Identification of a novel function of the mammalian Atg4 family during PINK1/Parkin mitophagy
11:25 – 11:40 Hugh Ma (Monash University)
  Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation
11:40 – 11:55 Ashleigh Solano (University of Melbourne)
  Mapping DNA target search in the nucleus of a living cell by pair correlation of molecular brightness microscopy 
11:55 – 12:10 Joanne Hildebrand (WEHI)
  Missense mutations in the MLKL brace region lead to lethal neonatal inflammation in mice and are present in high frequency in humans
12:10 – 1:30 Lunch + Poster Session A [+trade display]
Afternoon Session I:  Chairs:  Dr Vihandha Wickramasinghe (Peter Mac),  Dr Lan Nguyen (Monash University)
1:30 – 1:55 Invited Speaker: Jennifer Zenker (ARMI)
  Live imaging of microtubule remodelling controlling early mammalian development
1:55 – 2:10 Ashleigh Poh (ONJCRI)
  Co-targeting macrophages to improve anti-tumour responses to immunotherapy
1:10 – 2:25 Yilin Kang (University of Melbourne)
  Complex IV defects and oxidative stress underpin neuronal cell death in a neurodegenerative syndrome
2:25 – 2:40 William Smiles (St. Vincent's Institute)
  Palmitoyl-CoA Regulates Drp1 and Mitochondrial Fission by a Structural Mechanism Shared Amongst Metabolic Enzymes
2:40 – 2:55 Ishara Atukorala (La Trobe University)
  Extracellular vesicles in cross-species communication, metastasis and cancer progression
2:55 – 3:55 Afternoon tea + Poster Session B [+trade display]
Afternoon Session II:  Chair: A/Prof Jon Oakhill (St Vincent's Institute), Dr Michael Roy (WEHI)
3:55 – 4:20 Invited Speaker: Delphine Merino (ONJCRI)
  Tracking and targeting aggressive clones in metastatic triple negative breast cancer
4:20 – 4:35 Marta Portela Esteban (La Trobe University)
  WNT vampirization by glioblastoma promotes JNK/MMPs positive feedback loop to mediate glioma progression and neurodegeneration 
4:35 – 4:50 Haiyin Liu (University of Melbourne)
  Mechanism of cell surface MHC II regulation
4:50 – 5:20 Keynote Speaker: David Komander (WEHI)
  Ubiquitin signals in mitophagy
5:20 – 5:30 Closing and awards: Dr Doug Fairlie (ONJCRI)




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